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DURATION OF AXILLARY BRACHIAL PLEXUS BLOCK IN PATIENTS WITH DIABETES MELLITUS IS LONGER THAN IN HEALTHY CONTROLS: A PROSPECTIVE OBSERVATIONAL STUDY
ESRA Academy. Salviz E. Sep 8, 2016; 138212; 0029 Topic: Peripheral Nerve Blocks
Dr. Emine Aysu Salviz
Dr. Emine Aysu Salviz

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Abstract
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Background and Aims:

Patients with diabetes mellitus (DM) type 2 may have subclinical neuropathy. We performed this study to determine the difference in durations of axillary brachial plexus blocks (ABPBs) in patients with DM and without DM (NODM). Our hypothesis was that the sensory block duration would be delayed in patients with DM.

Methods:

Seventy-one patients, who scheduled for elective forearm and/or hand surgery, were enrolled to the study. They received ultrasound-guided ABPBs with the mixture of 10 mL lidocaine 2% and 20 mL bupivacaine 0.5%. Postoperatively, all patients received paracetamol 1gm q4 hours, as needed. Our primary endpoint was sensory block duration. Secondary endpoints were motor block duration, time-to-first pain (numeric rating scale (NRS) ≥4), NRS pain scores and rescue analgesic consumption (NRS ≥4) through the postoperative first 2 days.

Results:

Sixty-seven patients completed the study, 22 in Group DM and 45 in Group NODM (Figure 1). Patient characteristics and types of surgeries were presented in Table 1. The sensory and motor block durations were longer in DM group than in NODM group (773.5 [479-1155] min vs 375 [113-900] min; P<0.001 and 523 [205-955] min vs 300 [110-680] min; P<0.001). Time-to-first pain was 855 [590-1285] min in DM group and 500 [200-990] min in NODM group (P<0.001). NRS scores were significantly lower in DM group at 6th and 12th hours (P<0.001 and P=0.001, respectively). Paracetamol consumption was lower in DM group through the postoperative first 2 days.

Conclusions:

The presence of DM was associated with longer duration of the sensory block after ABPBs.

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