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PATIENT AND NURSE SATISFACTION WITH TWO NON-INVASIVE PATIENT CONTROLLED ANALGESIA TREATMENTS FOR ACUTE POST-OPERATIVE PAIN MANAGEMENT
ESRA Academy. Katz P. Sep 8, 2016; 138250; 0068 Topic: Patient Controlled Analgesia
Pablo Katz
Pablo Katz

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Abstract
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Background and Aims:

Patient and nurse satisfaction were analyzed in an exploratory analysis comparing a sufentanil sublingual delivery system (Zalviso®) versus a fentanyl iontophoretic transdermal system (Ionsys®), both non-invasive patient controlled analgesia treatments indicated for acute moderate to severe post-operative pain in hospital setting

Methods:

Literature searches were conducted from 2004 to 2015 by using the main databases (Embase, Medline, Cochrane registry) and to be included in the analysis, trials had to meet pre-defined eligibility criteria. Only active comparator studies were used in this analysis. An indirect treatment comparison (ITC) was performed in this analysis. Patient and nurse satisfaction with the device scores from the Ease of Care questionnaire (EOC) were analyzed.

Results:

Five studies were identified that could be included in this analysis. In all studies the active comparator was intra-venous patient controlled analgesia (i.v. PCA) with morphine. The results of the ITC in terms of patient overall satisfaction score were significantly in favour of Zalviso® (WMD: 0.31; 95% CI: 0.05 to 0.57). Furthermore the results of the nurse overall satisfaction score were also significantly in favour of Zalviso® (WMD: 0.27; 95% CI: 0.09 to 0.45). (Figure 1)

Conclusions:

Patient and nurse EOC questionnaires both resulted in higher satisfaction scores for Zalviso® compared to Ionsys®.

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