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EFFECT OF INTRAOPERATIVE KETAMINE INFUSION ON THE POSTOPERATIVE PAIN AFTER BILATERAL AXILLO-BREAST APPROACH (BABA) ROBOTIC OR ENDOSCOPIC THYROIDECTOMY: PRELIMINARY REPORT
ESRA Academy. Moon J. Sep 8, 2016; 138276
Topic: Acute Postoperative Pain - Postoperative & Perioperative Analgesia
Dr. Jee Youn Moon
Dr. Jee Youn Moon

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Abstract
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Background and Aims:

Robot or endoscopy- assisted thyroidectomy is frequently performed due to its excellent cosmesis and recovery profiles. However, postoperative pain after robot or endoscopy- assisted thyroidectomy is remained as concerns due to extent tissue dissection and tension during the operation. The aim of this study is to the effect of intraoperative ketamine infusion on postoperative pain control after robot or endoscopy - assisted thyroidectomy via bilateral axillo-breast approach.

 

Methods:

Thirty adult patients scheduled for robot or endoscopy- assisted thyroidectomy were randomized into control group (group A, n = 15) or ketamine group (group B, n = 15). After induction of anesthesia, patients in group A and B were infused with the same volume of normal saline and ketamine (1 mg/kg bolus, 60 μg/kg/h continuous infusion), respectively. Total intravenous anesthesia with propofol and remifentanil was used for the induction and maintenance of anesthesia. Pain scores (101-point numerical rating scale, 0 = no pain, 100 = the worst imaginable pain), the consumption of rescue analgesics, and other adverse effects were assessed postoperatively. 


Results:

Patients in group B showed less pain scores than those of group A in the neck and axillar area (P < 0.05). Rescue analgesics of group B was less required than that of group A after surgery though it did not reach statistical significance. There were no significant differences in other adverse effect including PONV, headache, and dizziness. 

Conclusions:

Intravenous ketamine infusion during the anesthesia effectively reduced postoperative pain scores and rescue analgesics without adverse events after robot or endoscopy - assisted thyroidectomy.

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