ESRA Academy. LEE J. Sep 8, 2016; 138310; 0138 Topic: Acute Postoperative Pain - Postoperative & Perioperative Analgesia

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Background and Aims:

Postoperative sore throat (POST) is a complication that undermines patient satisfaction and increases discomfort. The present study examined the effects of dexamethasone gargle and endotracheal tube cuff soaking on the incidence and severity of POST.


Ninety patients were randomly allocated into three groups undergoing laparoscopic cholecystectomy: 0.9% normal saline gargling and tube soaking (group C), 0.05% dexamethasone gargling and 0.9% normal saline tube soaking (group G), 0.9% normal saline gargling and 0.05% dexamethasone tube soaking (group S). The incidence and severity of POST were then assessed and recorded at 1, 3, 6, and 24 hours after surgery.


The incidence of POST was significantly lower in group G and group S at 3 hours after surgery compared to that in group C. At 6 hours after surgery, group S had a significantly lower incidence of POST than group C, and at 24 hours after surgery, both group G and group S had significantly lower incidences of POST than group C (P < 0.05). In addition, there were statistically significant differences in the severity of POST at 6 hours after surgery between group C and group S, and at 24 hours after surgery between group C and both group G and group S (P < 0.05).


Among patients receiving laparoscopic cholecystectomy, those who gargled with 0.05% dexamethasone solution and those whose endotracheal tube cuff was soaked in the same solution before intubation experienced significantly lower incidence and severity of POST than the control group.

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