ESRA Academy. Mekel-Bobrov N. Sep 8, 2016; 138428; 0276 Topic: NEUROPATHIC PAIN
Disclosure(s): Nitzan Mekel-Bobrov is a full time employee of Boston Scientific.
Dr. NItzan Mekel-Bobrov
Dr. NItzan Mekel-Bobrov

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Background and Aims:

Spinal cord stimulation (SCS) therapy in patients with chronic pain may not only improve pain intensity but may also reduce disability and increase activities of daily living (ADL). A recently introduced SCS paradigm using a 3-dimensional algorithm to customize stimulation (Neural Targeting SCS) has enabled SCS treatment of pain areas which have historically been challenging, such as low back pain. We describe here a large observational study to characterize real-world disability and physical, functional outcomes using Neural Targeting SCS out to 2 years post implant.


This sub-study of the larger LUMINA clinical study is a multi-center, consecutive, observational assessment of 100 subjects using Precision Spectra SCS (Boston Scientific Corporation) for chronic, intractable pain of the low back and/or legs out to 2 years post-implant. The majority of subjects in this sub-study (72%) reported severe pain at baseline. In addition, 62% percent of subjects reported only experiencing low back pain at baseline.


To date, significant reductions in Oswestry Disability Index (ODI) scores and Numeric Rating Scale (NRS) scores, with increases in walking tolerance and an approximately 90% satisfaction rate, have been observed. Relative to baseline, these reductions include a 21.3 point decrease in mean ODI score, a 51% increase in mean walking time, and a 3.3 point drop in mean NRS score.


In subjects with moderate or severe low back and/or leg pain, Neural Targeting SCS provided reduced disability (as measured by ODI and walking tolerance), reduced pain intensity (as measured by NRS), and produced generally high satisfaction rates.

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