ESRA Academy. J. Papadimos T. Sep 8, 2016; 138443; 0293 Topic: Thoracic Surgery - Analgesia after Thoracotomy - Cardiac Surgery- Vascular Surgery
Prof. Thomas J. Papadimos
Prof. Thomas J. Papadimos

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Background and Aims:

New data indicate that patients who receive RBC transfusions are more likely to have postoperative complications and increased risk of mortality. Studies suggest an association between transfusion in critically ill patients and poorer outcomes. Few studies have looked at the effects of transfusion, specifically in cardiac surgery patients.


The authors hypothesized that in a cohort of cardiac surgery transfused patients would have increased 30-day and 1-year mortality compared to non-transfused patients.


A retrospective quality analysis of 1,409 patients undergoing CABG surgery at OSUMC between 2008 and 2013 was performed. Data collection included: Patient demographics, baseline labs, transfusion timing, units transfused, postoperative labs, adverse events, length of stay (LOS), and 30-day and 1-year postoperative mortality. Continuous variables are expressed as mean ± (SD) and categorical variables, percentages.


Of the 1,409 patients analyzed, 717 patients received blood and 682 did not. The average units of RBCs given intraoperatively was 2.01  1.5 and postoperatively, 2.90  2.86. Transfused patients stayed 3.39 days longer than non-transfused patients. At 30 days post-op, 2.81% of transfused patients had died compared to 0.59% of non-transfused patients; by 1 year post-op, 13.87% of transfused patients had died compared to 3.59% of non-transfused patients.


Transfused CABG patients showed an increased LOS and 30-day and 1-year mortality. These outcomes may not be due to surgical complications, but rather to transfusion itself. Overall, RBC transfusion did not appear to improve outcomes for patients in this study

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