ESRA Academy. Zavridis P. Sep 8, 2016; 138472; 0330 Topic: PAIN THERAPY (ACUTE - CHRONIC)
Dr. Periklis Zavridis
Dr. Periklis Zavridis

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Background and Aims:

The objective of our study is to evaluate efficacy and safety of percutaneous computed tomography guided neurolysis with continuous or pulsed radiofrequency as palliative therapy for pain reduction in oncologic patients.


During the last 16 months, 22 patients (10 males, 12 females) underwent percutaneous CT guided neurolysis with continuous or pulsed radiofrequency for pain control. Malignant background included pancreatic carcinoma (n=8), pancoast tumor (n=5), renal cell(n=1), lymphoma (n=1), endometrial(n=2), colon(n=2) and ovarian (n=3) carcinoma. Patients underwent neurolysis by means of radiofrequency in celiac and splachnic plexus (n=9), in thoracic (n=1), in lumbar (n=2), in superior hypogastric plexus (n=5) and in stellate ganglion (n=5). Pain prior, one, two weeks  and 6 months later were compared by means of a numeric visual scale (NVS) for pain and Brief Pain Inventory (Short Form) questionaries. 


Comparing the pain scores prior (mean value 9.20 NVS, range 7-10 NVS), one week later (mean value 7.1 NVS range 4-9 NVS), two weeks later (mean value 3.8 NVS range 2-7 NVS) and six months after the treatment (mean value 5.9 NVS range 2-9 NVS) there was significant mean pain reduction and life quality improvement. Overall mobility improved in 18/22 (82%) patients. No complication was observed.


Radiofrequency ablation (pulsed or continuous) for percutaneous neurolysis under CT guidance is a safe and efficient technique for pain palliation in oncologic patients.

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