ESRA Academy. Alp H. Sep 8, 2016; 138546; 0414 Topic: PAIN THERAPY (ACUTE - CHRONIC)
Assoc. Prof. Hayriye Alp
Assoc. Prof. Hayriye Alp

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Background and Aims:

POEMS ; It is a paraneoplastic syndrome. It is include papilledema, thrombocytosis, polycythemia, pulmonary diseases hipertansiyon. In mayo clinic research ,it was detected in all  of the plasma discresia by 1.4% of clinical series. In the pathogenesis, vascular endothelial growth factor (VEGF), an important place the most important and immutable characteristic featureof syndrome’s  is chronic progressive neuropathy


39-year-old female patient body itching, was admitted to the hematology department due to night sweats and weight loss. There was no abnormality in the family history. The patient underwent chemotherapy at the end of tests was diagnosed with plasma cell dyscrasias. axonal neuropathy occurred in the biopsy of the limb swelling was observed.  There were stinging burning painestioning of diseases of the skin darkens and learned that increase skin dryness.  we were learned that she was have to use vegetable  moisturizers. The patient was underwent regular three day program to strengthen the muscles with workouts per week. Tramadol drops were recommended for the period of 5 Vas. PET scan was  normal.


Poems Syndrome incidence peaks in the 5th and 6th decades. The differential diagnosis of monoclonal gammopathy unmeasurable level (MGUS), CIDP, primary systemic amyloidosis and is located krioglobuline 


In  all of the poems  cases there is a peripheral neuropathy that is very evident in the clinical picture. Motor involvement is followed by sensory symptoms. Symptoms start from the feet, numbness, tingling and cold would feel. And a distal symmetric neuropathy involvement exhibitions, spread proximally showing progress. Some patients suffer from pain .

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