Save
EFFECT OF PERINEURAL DEXAMETHASONE WITH BUPIVACAINE IN SINGLE SPACE PARAVERTEBRAL BLOCK FOR POSTOPERATIVE ANALGESIA IN ELECTIVE NEPHRECTOMY CASES: A DOUBLE BLIND PLACEBO CONTROLLED TRIAL
ESRA Academy. Tomar G. Sep 8, 2016; 138601; 0482 Topic: Thoracic Paravertebral and Intercostal Blocks
Dr. Gaurav Tomar
Dr. Gaurav Tomar

Access to Premium content is currently a membership benefit.


Click here to join ESRA or renew your membership.

Abstract
Discussion Forum (0)
Rate & Comment (0)
Background and Aims:

Peripheral nerve block especially paravertebral block using local anaesthetic along with perineural steroids as adjuvant may prove promising. Aim of this study is to assess the efficacy of dexamethasone with bupivacaine as adjuvant for single bolus injection of thoracic paravertebral block in patients undergoing elective nephrectomy.

Methods:

60 patients of ASA physical status I and II were randomly assigned to two groups of 30 patients each. Group D patients received 8 mg (2 ml) of dexamethasone mixed to 18 ml of 0.25% bupivacaine while in group B, patients received 18 ml of 0.25% bupivacaine and 2 ml of 0.9% saline as placebo to make a total volume 20 ml solution infiltrated in paravertebral block. Degree of analgesia achieved and duration of analgesia was recorded in each group along with total dose requirement of rescue analgesic and side effects in 1st 24 hours postoperatively.

Results:

Group D patients with dexamethasone had VAS score of (0-3) after 09 minutes of block up to 610.48±12.24 minutes and after 16 minutes up to 402.34±28.12 minutes in another group B respectively. The total dose of IV fentanyl in first 24 hours in postoperative period in group D was 98.6±14.14 μg as compared to 147.6±18.22 μg in group B. No other significant side effects were noted except for nausea and vomiting in 5 patients of placebo group.

Conclusions:

Dexamethasone along with bupivacaine as adjunct for thoracic paravertebral block, helps in improving the quality and enhancing the postoperative analgesia duration in patients undergoing nephrectomy.  

Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings