Save
Application of Pre-emptive analgesia strategy for operative procedures
Author(s):
saad, A.*
Affiliations:
ahamdi hospital, anesthesia, ahamdi, Kuwait
ESRA Academy. Saad A. Sep 13, 2017; 190722; 508 Topic: PAIN THERAPY (ACUTE - CHRONIC)
Login now to access Regular content available to all registered users.

Access to Premium content is currently a membership benefit.


Click here to join ESRA or renew your membership.


Abstract
Discussion Forum (0)
Rate & Comment (0)
Background and Aims:

Pain from surgical procedures occurs as a consequence of tissue trauma and may result in physical, cognitive, and emotional discomfort.  Pre-emptive analgesia focuses on postoperative pain control and the prevention of central sensitization and chronic neuropathic pain by providing analgesia administered preoperatively but not after surgical incision.
--aim; To study the effect of oral gabapentin used as preemptive analgesia to attenuate post operative pain

Methods:

In a randomized double blind study, 40 patients were given Lyrica 75 mg 2hr preop +/- Celebrex 200mg PO CAP. 2hr preop. +/- zantac 150mg PO tab. 2hr preoperative then postoperative; Lyrica 75 mg at night HS + Celebrex 200mg PO CAP. BD +/- Solpadine 2tab. QID post. Op

Combined with regional anaesthesia (spinal/epidural), intraoperative local anaesthetic infiltration and some slow release post operative analgesia, my experience is that patients are more comfortable post op, able to mobilise much quicker and achieve an earlier and more comfortable discharge from hospital.

Results:

Time for rescue analgesia (VAS score >3) was significantly increased in most patients given lyrica preoperative and postoperative with NSAIDs. The sedation scores and patient satisfaction scores were also more with Lyrica, NSAIDs.

Conclusions:

Preemptive pregabalin in an oral dose of 75-150mg offers good postoperative analgesia in lower limb orthopedic surgeries under spinal anesthesia. pre-emptive oral pregabalin reduces diclofenac requirement post-operatively which was significantly lower as compared to placebo group. single dose preoperative pregabalin improves analgesia in early postoperative period and reduces analgesic consumption but with increased sedation without respiratory depression. use of narcotics less after preemptive protocol

Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings